O desenvolvimento de um sistema de escore prognóstico em pediatria requer clareza, facilidade, variáveis relevantes, aderência a metodologia padrão e especificidade.

The course aims to expand knowledge in the field of protein kinases and related signaling pathways. To this end, the following topics will be addressed: (1) The study of kinase signaling cascades and their functions; tyrosine kinase coupled receptors; (2) Kinases as pharmacological targets (3) Main enzyme mechanisms of kinases; (4) Strategies for the design of new molecules and types of inhibitors.